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What filter does a Honeywell HE225 take?

It takes the Honeywell HC22E1003 AgION Pad (AprilAire #45 fit) — OEM part number HC22E1003.

Honeywell HE225, whole-house humidifier, whole house.

Lowest verified price: $15.50 — aftermarket, 2-pack replacement for HC22E1003 at DiscountFilters. Free shipping on orders $70+ at DiscountFilters; a fee applies below that. Checked 2026-11-11.
Buy the HC22E1003 on Amazon — HC22E1003Amazon search for the exact part number (no single listing is endorsed). Amazon price is shown on Amazon; we do not quote it here.

The part, in brief

PartHoneywell HC22E1003 AgION Pad (AprilAire #45 fit)
Replacement intervalReplace annually.
Per changeSold as a 2-pack at DiscountFilters.
EquivalentsAprilAire 45, BestAir A45

Verified prices

OptionPriceStore & shipping
Genuine (OEM)
2-pack, genuine Honeywell HC22E1003 ($9.48 per panel)
$18.95DiscountFilters
Free shipping on orders $70+ at DiscountFilters; a fee applies below that · Checked 2026-11-11 · source
Aftermarket
2-pack replacement for HC22E1003
$15.50DiscountFilters
Free shipping on orders $70+ at DiscountFilters; a fee applies below that · Checked 2026-11-11 · source

Full record with every price, source and date: Honeywell HC22E1003 AgION Pad (AprilAire #45 fit) page.

Finding the model number on a Honeywell

Model numbers are on the bottom of the base or on a sticker on the back of the tower. The letter at the end is the color: B = black, W = white (for example HEV615B is the black tower, HEV615W the white one). Filter letters: A = HAC-504, T = HFT600, R = HAC-504AW-class refill.