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Honeywell HC22E1003 AgION Pad (AprilAire #45 fit)

OEM part number(s): HC22E1003, HC22E · Made by Honeywell · Whole-house water panel / pad

Lowest verified price: $15.50 — aftermarket, 2-pack replacement for HC22E1003 at DiscountFilters. Free shipping on orders $70+ at DiscountFilters; a fee applies below that. Checked 2026-11-11.

Buy on Amazon — HC22E1003Amazon search for the exact part number (no single listing is endorsed). Amazon price is shown on Amazon; we do not quote it here.

Verified prices (checked 2026-11-11)

Option	Price	Store & shipping
Genuine (OEM) 2-pack, genuine Honeywell HC22E1003 ($9.48 per panel)	$18.95	DiscountFilters Free shipping on orders $70+ at DiscountFilters; a fee applies below that · Checked 2026-11-11 · source
Aftermarket 2-pack replacement for HC22E1003	$15.50	DiscountFilters Free shipping on orders $70+ at DiscountFilters; a fee applies below that · Checked 2026-11-11 · source

How to read this: the lowest verified price above is the headline even when it is not Amazon. Amazon is the buy button because it is this site's affiliate route; its price is not quoted because Amazon blocks automated price reads.

Exact fit — models that take this part

Honeywell HE105, Honeywell HE220, Honeywell HE225

How many per change: Sold as a 2-pack at DiscountFilters.

Specifications

Replacement interval	Replace annually.
Dimensions	10 × 13 × 1.75 in
Treatment	AgION antimicrobial coated (Honeywell).

Equivalents and cross-references

Brand	Part number	Note
AprilAire	45	Honeywell's cross-reference: HC22E1003 replaces the AprilAire 45 (and also cross-references the discontinued #30). See the AprilAire #45 record.
BestAir	A45	BestAir equivalent family.

Sources

https://www.discountfilters.com/humidifier-pads/honeywell-hc22e1003-humidifier-filter-2pack/p186023/

Full record, including descriptor data for every model, is in the open dataset: /data/parts.json.